MOLECULAR DE-NOVO DESIGN THROUGH DEEP REINFORCEMENT LEARNING

Molecular de-novo design through deep reinforcement learning

Abstract This work introduces a method to tune a sequence-based generative model for molecular de novo design that through augmented episodic likelihood can learn to generate structures with certain specified desirable properties.We demonstrate how this model can execute a range of tasks such as generating analogues to a query structure and generat

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Safety and efficacy of auricular acupuncture in patients with depression after percutaneous coronary intervention

Abstract.Background:.With the advantages of miniature damage and optimal effectiveness, percutaneous coronary intervention (PCI) has been performed in a large number of coronary artery disease patients.However, recent studies have indicated a higher incidence of depression on post-PCI patients.Acupuncture therapy is effective for depression.As a fo

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Acceptability of emergency contraception in Brazil, Chile, and Mexico: 1 - Perceptions of emergency oral contraceptives

This article presents the results of a study on the acceptability of emergency contraception (EC) in Brazil, Chile, and Mexico.Opinions of potential users and possible Suspension Strap Kit providers were obtained through discussion groups and those of authorities and policy-makers through semi-structured interviews.Most participants had a positive

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